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  <xs:element id="ddog_DeferredContractCostsPolicyPolicyTextBlock" abstract="false" name="DeferredContractCostsPolicyPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ddog_WeightedAverageRemainingLeaseTermAndDiscountRateLesseeTableTextBlock" abstract="false" name="WeightedAverageRemainingLeaseTermAndDiscountRateLesseeTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ddog_AdjustmentsToAdditionalPaidInCapitalPurchasesOfCappedCallsRelatedToConvertibleDebt" abstract="false" name="AdjustmentsToAdditionalPaidInCapitalPurchasesOfCappedCallsRelatedToConvertibleDebt" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ddog_ScheduleOfFiniteLivedAssetsEstimatedUsefulLivesTableTextBlock" abstract="false" name="ScheduleOfFiniteLivedAssetsEstimatedUsefulLivesTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="ddog_CostIncurredToPurchaseCappedCalls" abstract="false" name="CostIncurredToPurchaseCappedCalls" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ddog_StockIssuedDuringPeriodSharesVestingOfRestrictedStockUnits" abstract="false" name="StockIssuedDuringPeriodSharesVestingOfRestrictedStockUnits" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ddog_CommonStockCoveredUnderCappedCallsTransaction" abstract="false" name="CommonStockCoveredUnderCappedCallsTransaction" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ddog_A2012EquityIncentivePlanMember" abstract="true" name="A2012EquityIncentivePlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ddog_ContingentFederalPayrollTaxLiability" abstract="false" name="ContingentFederalPayrollTaxLiability" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ddog_DebtInstrumentConvertibleTermsDomain" abstract="true" name="DebtInstrumentConvertibleTermsDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ddog_DeferredTaxAssetsCapitalization" abstract="false" name="DeferredTaxAssetsCapitalization" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ddog_ScenarioOneMember" abstract="true" name="ScenarioOneMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ddog_OtherNonoperatingIncomeExpenseNet" abstract="false" name="OtherNonoperatingIncomeExpenseNet" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ddog_CommonStockIssuedSubjectToRepurchaseRelatedToEarlyExerciseOfOptions" abstract="false" name="CommonStockIssuedSubjectToRepurchaseRelatedToEarlyExerciseOfOptions" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ddog_DebtInstrumentConvertibleMeasurementPeriod" abstract="false" name="DebtInstrumentConvertibleMeasurementPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="ddog_EmployeeStockOptionAndRestrictedStockUnitsMember" abstract="true" name="EmployeeStockOptionAndRestrictedStockUnitsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ddog_AcquisitionIntangibleAssetsAndGoodwillLineItems" abstract="true" name="AcquisitionIntangibleAssetsAndGoodwillLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="ddog_ReallocationOfUndistributedIncomeLossResultOfConversionOfCommonStock" abstract="false" name="ReallocationOfUndistributedIncomeLossResultOfConversionOfCommonStock" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ddog_UnvestedEarlyExercisedStockOptionsAndRestrictedStockMember" abstract="true" name="UnvestedEarlyExercisedStockOptionsAndRestrictedStockMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ddog_DeferredTaxLiabilitiesCommissions" abstract="false" name="DeferredTaxLiabilitiesCommissions" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ddog_LongLivedAssetsMember" abstract="true" name="LongLivedAssetsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ddog_OperatingLeaseNonCashLeaseExpense" abstract="false" name="OperatingLeaseNonCashLeaseExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ddog_DebtInstrumentConvertibleTermsAxis" abstract="true" name="DebtInstrumentConvertibleTermsAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="ddog_DebtIssuanceCostAttributableToLiabilityComponent" abstract="false" name="DebtIssuanceCostAttributableToLiabilityComponent" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ddog_AccruedEarlyExerciseLiabilityStockOptions" abstract="false" name="AccruedEarlyExerciseLiabilityStockOptions" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ddog_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfEquityIncentivePlan" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfEquityIncentivePlan" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="ddog_SharesAvailableForFutureEmployeeStockOptionAndRestrictedStockUnitsGrantsMember" abstract="true" name="SharesAvailableForFutureEmployeeStockOptionAndRestrictedStockUnitsGrantsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ddog_BusinessCombinationNumberOfPurchaseAgreements" abstract="false" name="BusinessCombinationNumberOfPurchaseAgreements" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
</xs:schema>
